Showing 50 of 407 results
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- MPRA in WTC11Elements cloned into the lentiMPRA vector upstream of a minimal promoter, with barcode located in the 5' UTR of the reporter. Elements test neuronal enhancers and promoters.Lab: Nadav Ahituv, UCSFProject: ENCODE
- MPRA in K562Homo sapiens K562, 24 hours post-nucleic acid delivery time genetically modified (episome) using transient transfectionLab: Ryan Tewhey, JAXProject: ENCODE
- MPRA in K562Homo sapiens K562, 24 hours post-nucleic acid delivery time genetically modified (episome) using transient transfectionLab: Ryan Tewhey, JAXProject: ENCODE
- MPRA in K562Homo sapiens K562, 24 hours post-nucleic acid delivery time genetically modified (episome) using transient transfectionLab: Ryan Tewhey, JAXProject: ENCODE
- MPRA in WTC11Elements cloned into the lentiMPRA vector upstream of a minimal promoter, with barcode located in the 5' UTR of the reporter. Elements test potential HepG2, K562, and WTC11 enhancers and promoters of all protein-coding genes.Lab: Nadav Ahituv, UCSFProject: ENCODE
- MPRA in K562Elements cloned into the lentiMPRA vector upstream of a minimal promoter, with barcode located in the 5' UTR of the reporter. Elements test potential HepG2, K562, and WTC11 enhancers and promoters of all protein-coding genes.Lab: Nadav Ahituv, UCSFProject: ENCODE
- MPRA in WTC11Elements cloned into the lentiMPRA vector upstream of a minimal promoter, with barcode located in the 5' UTR of the reporter. Elements test potential WTC11 enhancers and promoters of protein-coding genes.Lab: Nadav Ahituv, UCSFProject: ENCODE
- STARR-seq in K562Homo sapiens K562 genetically modified (episome) using transient transfectionElements selection method: accessible genome regionsLab: Tim Reddy, DukeProject: ENCODE
- STARR-seq in glutamatergic neuronHomo sapiens glutamatergic neuron, 7 days post differentiation genetically modified (episome) using transient transfection, (insertion) using TALEN inserting M. musculus Neurog2Lab: Kevin White, UChicagoProject: ENCODE
- MPRA of TERT locus in glial cellElements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the TERT promoter.
- MPRA of TERT locus in glial cellElements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the TERT promoter.
- MPRA of TERT locus in glial cellElements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the TERT promoter.
- MPRA of PKLR locus in K562Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the PKLR promoter.
- MPRA of PKLR locus in K562Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the PKLR promoter.
- MPRA of MYC locus in LNCAPElements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the MYC enhancer around SNP rs11986220.
- MPRA of IRF6 locus in HaCaTElements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the IRF6 enhancer.
- MPRA of IRF4 locus in SK-MEL-28Elements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the IRF4 enhancer.
- MPRA of HBG1 locus in HELElements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the HBG1 promoter.
- MPRA of HBB locus in HELElements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the HBB promoter.
- MPRA of GP1BB locus in HELElements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the GP1BB promoter.
- MPRA of FOXE1 locus in HeLaElements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the FOXE1 promoter.
- MPRA of BCL11A locus in HELElements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the BCL11A enhancer.
- CRISPR cutting CRISPR screen of GATA1 locus in K562CRISPR screen targeting candidate CREs following survival
- CRISPR cutting CRISPR screen of GATA1 locus in K562CRISPR screen targeting candidate CREs following survival
- CRISPR cutting CRISPR screen of GATA1 locus in K562Control for CRISPR screen targeting candidate CREs
- CRISPR cutting CRISPR screen of GATA1 locus in K562Control for CRISPR screen targeting candidate CREs
- MPRA in K562Homo sapiens K562, 24 hours post-nucleic acid delivery time genetically modified (episome) using transient transfectionElements selection method: sequence variantsLab: Ryan Tewhey, JAXProject: ENCODE
- CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of MYBHomo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple lociTiling modality: full tilingLab: Pardis Sabeti, BroadProject: ENCODE
- CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of MYBHomo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple lociTiling modality: full tilingLab: Pardis Sabeti, BroadProject: ENCODE
- CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of HBS1LHomo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple lociTiling modality: full tilingLab: Pardis Sabeti, BroadProject: ENCODE
- CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of HBS1LHomo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple lociTiling modality: full tilingLab: Pardis Sabeti, BroadProject: ENCODE
- CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of HBE1Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple lociTiling modality: full tilingLab: Pardis Sabeti, BroadProject: ENCODE
- CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of HBE1Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple lociTiling modality: full tilingLab: Pardis Sabeti, BroadProject: ENCODE
- CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of HBG2Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple lociTiling modality: full tilingLab: Pardis Sabeti, BroadProject: ENCODE
- CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of HBG2Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple lociTiling modality: full tilingLab: Pardis Sabeti, BroadProject: ENCODE
- CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of HBG1Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple lociTiling modality: full tilingLab: Pardis Sabeti, BroadProject: ENCODE
- CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of HBG1Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple lociTiling modality: full tilingLab: Pardis Sabeti, BroadProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for CRISPRi/dCas9-RYBP sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Elements selection method: DNase hypersensitive sitesTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for CRISPRi/dCas9-KRAB-WSR7EEE sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Elements selection method: DNase hypersensitive sitesTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for CRISPRi/dCas9-RYBP sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Elements selection method: DNase hypersensitive sitesTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for CRISPRi/dCas9-KRAB-WSR7EEE sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Elements selection method: DNase hypersensitive sitesTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for CRISPRi/dCas9-KRAB-MGA1-MGA2 sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Elements selection method: DNase hypersensitive sitesTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for dCas9-ZNF705-KRAB/CRISPRi tiling proliferation screens at a subset of cCREs around essential genesElements selection method: DNase hypersensitive sitesTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for dCas9-RYBP/CRISPRi tiling proliferation screens at a subset of cCREs around essential genesElements selection method: DNase hypersensitive sitesTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for dCas9-KRAB-WSR7EEE/CRISPRi tiling proliferation screens at a subset of cCREs around essential genesElements selection method: DNase hypersensitive sitesTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for dCas9-KRAB/CRISPRi tiling proliferation screens at a subset of cCREs around essential genesElements selection method: DNase hypersensitive sitesTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPR dCas proliferation screen in K562Functional characterization experiment for dCas9 tiling proliferation screens at a subset of cCREs around essential genesElements selection method: DNase hypersensitive sitesTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPR cutting proliferation screen of CTCF locus in K562Functional characterization experiment for Cas9/CRISPR fine-mapping proliferation screens at hit and non-hit CTCF motifs in loop anchors (and their partner anchors) from the CTCF growth screenElements selection method: TF binding sitesLoci: CTCFTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPR cutting proliferation screen of CTCF locus in K562Functional characterization experiment for Cas9/CRISPR fine-mapping proliferation screens at hit and non-hit CTCF motifs in loop anchors (and their partner anchors) from the CTCF growth screenElements selection method: TF binding sitesLoci: CTCFTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPR cutting proliferation screen of CTCF locus in K562Functional characterization experiment for tiling, Cas9/CRISPRk proliferation screens at CTCF motifs in loop anchorsElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE