Showing 50 of 59 results
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- proliferation CRISPR screen in glutamatergic neuronHomo sapiens glutamatergic neuron, 14 days post differentiation genetically modified (CRISPRi) using CRISPR, (insertion) using CRISPR, (insertion) using TALEN inserting M. musculus Neurog2Lab: Yin Shen, UCSFProject: ENCODE
- proliferation CRISPR screen in neural progenitor cellHomo sapiens neural progenitor cell, 3 days post differentiation genetically modified (CRISPRi) using CRISPR, (insertion) using CRISPR, (insertion) using TALEN inserting M. musculus Neurog2Lab: Yin Shen, UCSFProject: ENCODE
- proliferation CRISPR screen in WTC11Homo sapiens WTC11, 0 days post differentiation genetically modified (CRISPRi) using CRISPR, (insertion) using CRISPR, (insertion) using TALEN inserting M. musculus Neurog2Lab: Yin Shen, UCSFProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for CRISPRi/dCas9-RYBP sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Elements selection method: DNase hypersensitive sitesTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for CRISPRi/dCas9-KRAB-WSR7EEE sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Elements selection method: DNase hypersensitive sitesTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for CRISPRi/dCas9-RYBP sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Elements selection method: DNase hypersensitive sitesTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for CRISPRi/dCas9-KRAB-WSR7EEE sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Elements selection method: DNase hypersensitive sitesTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for CRISPRi/dCas9-KRAB-MGA1-MGA2 sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Elements selection method: DNase hypersensitive sitesTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for dCas9-ZNF705-KRAB/CRISPRi tiling proliferation screens at a subset of cCREs around essential genesElements selection method: DNase hypersensitive sitesTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for dCas9-RYBP/CRISPRi tiling proliferation screens at a subset of cCREs around essential genesElements selection method: DNase hypersensitive sitesTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for dCas9-KRAB-WSR7EEE/CRISPRi tiling proliferation screens at a subset of cCREs around essential genesElements selection method: DNase hypersensitive sitesTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen in K562Functional characterization experiment for dCas9-KRAB/CRISPRi tiling proliferation screens at a subset of cCREs around essential genesElements selection method: DNase hypersensitive sitesTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPR dCas proliferation screen in K562Functional characterization experiment for dCas9 tiling proliferation screens at a subset of cCREs around essential genesElements selection method: DNase hypersensitive sitesTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPR cutting proliferation screen of CTCF locus in K562Functional characterization experiment for Cas9/CRISPR fine-mapping proliferation screens at hit and non-hit CTCF motifs in loop anchors (and their partner anchors) from the CTCF growth screenElements selection method: TF binding sitesLoci: CTCFTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPR cutting proliferation screen of CTCF locus in K562Functional characterization experiment for Cas9/CRISPR fine-mapping proliferation screens at hit and non-hit CTCF motifs in loop anchors (and their partner anchors) from the CTCF growth screenElements selection method: TF binding sitesLoci: CTCFTiling modality: peak tilingLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPR cutting proliferation screen of CTCF locus in K562Functional characterization experiment for tiling, Cas9/CRISPRk proliferation screens at CTCF motifs in loop anchorsElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPR cutting proliferation screen of CTCF locus in K562Functional characterization experiment for tiling, Cas9/CRISPRk proliferation screens at CTCF motifs in loop anchorsElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen of CTCF locus in K562Functional characterization experiment for tiling, dCas9-KRAB/CRISPRi proliferation screens at CTCF motifs in loop anchorsElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRi proliferation screen of CTCF locus in K562Functional characterization experiment for tiling, dCas9-KRAB/CRISPRi proliferation screens at CTCF motifs in loop anchorsElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPR dCas proliferation screen of CTCF locus in K562Functional characterization experiment for tiling, dCas9/CRISPRd proliferation screens at CTCF motifs in loop anchorsElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPR dCas proliferation screen of CTCF locus in K562Functional characterization experiment for tiling, dCas9/CRISPRd proliferation screens at CTCF motifs in loop anchorsElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRa proliferation screen of CTCF locus in K562Functional characterization experiment for tiling, dCas9-VPR/CRISPRa proliferation screens at CTCF motifs in loop anchorsElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPRa proliferation screen of CTCF locus in K562Functional characterization experiment for tiling, dCas9-VPR/CRISPRa proliferation screens at CTCF motifs in loop anchorsElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peakLab: Will Greenleaf, StanfordProject: ENCODE
- CRISPR dCas proliferation screen of multiple loci in K562Tiling, dCas9/CRISPRd proliferation screen at the GATA1, MYB, and ZMYND8 loci
- CRISPR dCas proliferation screen of multiple loci in K562Tiling, dCas9/CRISPRd proliferation screen at the GATA1, MYB, and ZMYND8 loci
- CRISPRa proliferation screen of multiple loci in K562Tiling, dCas9-VPR/CRISPRa proliferation screen at the GATA1, MYB, and ZMYND8 loci
- CRISPRa proliferation screen of multiple loci in K562Tiling, dCas9-VPR/CRISPRa proliferation screen at the GATA1, MYB, and ZMYND8 loci
- CRISPR cutting proliferation screen of multiple loci in K562Tiling, Cas9/CRISPRk proliferation screen at the GATA1, MYB, and ZMYND8 loci
- CRISPR cutting proliferation screen of multiple loci in K562Tiling, Cas9/CRISPRk proliferation screen at the GATA1, MYB, and ZMYND8 loci
- CRISPRi proliferation screen of multiple loci in K562Tiling, dCas9-KRAB/CRISPRi proliferation screen at the GATA1, MYB, and ZMYND8 loci
- CRISPRi proliferation screen of multiple loci in K562Tiling, dCas9-KRAB/CRISPRi proliferation screen at the GATA1, MYB, and ZMYND8 loci
- CRISPRi proliferation screen in K562Homo sapiens K562, 14 days post-nucleic acid delivery time genetically modified (insertion) using transduction, using CRISPRi (pgRNA)Elements selection method: histone modificationsTiling modality: peak tilingLab: Bing Ren, UCSDProject: ENCODE
- CRISPRi proliferation screen in HCT116Homo sapiens HCT116, 14 days post-nucleic acid delivery time genetically modified (insertion) using transduction, using CRISPRi (pgRNA)Elements selection method: histone modificationsTiling modality: peak tilingLab: Bing Ren, UCSDProject: ENCODE
- CRISPRi proliferation screen in HCT116Homo sapiens HCT116, 14 days post-nucleic acid delivery time genetically modified (insertion) using transduction, using CRISPRi (pgRNA)Elements selection method: histone modificationsTiling modality: peak tilingLab: Bing Ren, UCSDProject: ENCODE
- CRISPRi proliferation screen in K562Homo sapiens K562, 0 days post-nucleic acid delivery time genetically modified (insertion) using transduction, using CRISPRi (pgRNA)Elements selection method: histone modificationsTiling modality: peak tilingLab: Bing Ren, UCSDProject: ENCODE
- CRISPRi proliferation screen in HCT116Homo sapiens HCT116, 0 days post-nucleic acid delivery time genetically modified (insertion) using transduction, using CRISPRi (pgRNA)Elements selection method: histone modificationsTiling modality: peak tilingLab: Bing Ren, UCSDProject: ENCODE
- CRISPRi proliferation screen in HCT116Homo sapiens HCT116, 0 days post-nucleic acid delivery time genetically modified (insertion) using transduction, using CRISPRi (pgRNA)Elements selection method: histone modificationsTiling modality: peak tilingLab: Bing Ren, UCSDProject: ENCODE
- CRISPR cutting proliferation screen of GATA1 locus in K562CRISPR screen targeting candidate CREs following survival
- CRISPR cutting proliferation screen of GATA1 locus in K562Control for CRISPR screen targeting candidate CREs
- CRISPR cutting proliferation screen of MYC locus in K562CRISPR screen targeting candidate CREs following survival
- CRISPRi proliferation screen in OCI-AML2CRISPR-dCas9-based epigenomic regulatory element screening (CERES) technology to screen a subset of putative non-coding regulatory elements identified in human K562 leukemia cells from whole genome discovery screen (validation). This validation screen was performed in OCI-AML2 acute myeloid leukemia cellsTiling modality: sparse peakLab: Tim Reddy, DukeProject: ENCODE
- CRISPRi proliferation screen in K562CRISPR-dCas9-based epigenomic regulatory element screening (CERES) technology to screen a subset of putative non-coding regulatory elements identified in human K562 leukemia cells from whole genome discovery screen (validation). This validation screen was performed in K562 leukemia cellsTiling modality: sparse peakLab: Tim Reddy, DukeProject: ENCODE
- CRISPRi proliferation screen in K562CRISPR-dCas9-based epigenomic regulatory element screening (CERES) technology to screen all >100,000 putative non-coding regulatory elements defined by open chromatin sites in human K562 leukemia cells for their role in regulating essential cellular processes (whole genome).Tiling modality: peak tilingLab: Tim Reddy, DukeProject: ENCODE
- CRISPR cutting proliferation screen of multiple loci in WTC11Cell survival-based CRISPR screen targeting genomic regions near MSH2, MSH6, MLH1, PMS2, PCNA and HPRT1 genes.
- CRISPR cutting proliferation screen of multiple loci in WTC11Cell survival-based CRISPR screen targeting genomic regions near MSH2, MSH6, MLH1, PMS2, PCNA and HPRT1 genes.
- CRISPR cutting proliferation screen of multiple loci in WTC11Cell survival-based CRISPR screen targeting genomic regions near MSH2, MSH6, MLH1, PMS2, PCNA and HPRT1 genes.
- CRISPRi proliferation screen of multiple loci in WTC11Cell survival-based CRISPR screen targeting genomic regions near MSH2, MSH6, MLH1, PMS2, PCNA and HPRT1 genes.
- CRISPRi proliferation screen of multiple loci in WTC11Cell survival-based CRISPR screen targeting genomic regions near MSH2, MSH6, MLH1, PMS2, PCNA and HPRT1 genes.
- CRISPRi proliferation screen of multiple loci in WTC11Cell survival-based CRISPR screen targeting genomic regions near MSH2, MSH6, MLH1, PMS2, PCNA and HPRT1 genes.
- CRISPRi proliferation screen of multiple loci in PC-3Growth-based CRISPR screen targeting genomic regions near MYC and MYB genes.