Summary for ENCSR179FSH
Summary
- Status
- released
- Description
- Functional characterization series of CRISPRi (dCas9-KRAB) growth screen targeting putative essential DHSs in K562. (validation screen in OCI-AML2).
- Donor diversity
- single
- Assay
- proliferation CRISPR screen
- Biosample summary
- OCI-AML2 cell line genetically modified (insertion) using transduction, genetically modified (CRISPRi) using CRISPR
- Diseases
- Not reported
- Elements references
- Tiling modality
- sparse peak
Attribution
ENCODE4 project
- Lab
- Tim Reddy, Duke
- Award
- UM1HG009428 (Tim Reddy, Duke)
- Project
- ENCODE
- Aliases
- charles-gersbach:encode4-ceres-validation-screen-ociaml2-series
- External resources
- None submitted
- References
Experiments in ENCSR179FSH
Experiments
1 experiment
Accession | Assay | Examined loci | Biosample summary | Lab | Status | Cart |
|---|---|---|---|---|---|---|
| ENCSR689KVW | proliferation CRISPR screen | Homo sapiens OCI-AML2 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) | Tim Reddy, Duke | released |
Control experiments
1 control experiment
Accession | Control type | Biosample summary | Lab | Status | Cart |
|---|---|---|---|---|---|
| ENCSR770ENU | control | Homo sapiens OCI-AML2 genetically modified (insertion) using transduction | Tim Reddy, Duke | released |