Summary for ENCSR737MRW
Summary
- Status
- released
- Description
- Functional characterization series for tiling CRIPSRi proliferation screens at genome-wide cCREs essential for neuronal differentiation
- Donor diversity
- single
- Assay
- proliferation CRISPR screen
- Biosample summary
- DNA cloning sample cloning host, WTC11 cell line, neural progenitor cell in vitro differentiated cells, glutamatergic neuron in vitro differentiated cells genetically modified (insertion) using CRISPR, genetically modified (insertion) using TALEN inserting M. musculus Neurog2, genetically modified (CRISPRi) using CRISPR
- Diseases
- Not reported
- Elements references
Attribution
ENCODE4 project
- Lab
- Yin Shen, UCSF
- Award
- UM1HG009402 (Yin Shen, UCSF)
- Project
- ENCODE
- Aliases
- yin-shen:neuronal_differentiation_fCRE_screen
- External resources
- None submitted
Experiments in ENCSR737MRW
Experiments
4 experiments
Accession | Assay | Examined loci | Biosample summary | Lab | Status | Cart |
|---|---|---|---|---|---|---|
| ENCSR699JJN | pooled clone sequencing | Yin Shen, UCSF | released | |||
| ENCSR536LLM | proliferation CRISPR screen | Homo sapiens WTC11, 0 days post differentiation genetically modified (CRISPRi) using CRISPR, (insertion) using CRISPR, (insertion) using TALEN inserting M. musculus Neurog2 | Yin Shen, UCSF | released | ||
| ENCSR406XUG | proliferation CRISPR screen | Homo sapiens neural progenitor cell, 3 days post differentiation genetically modified (CRISPRi) using CRISPR, (insertion) using CRISPR, (insertion) using TALEN inserting M. musculus Neurog2 | Yin Shen, UCSF | released | ||
| ENCSR800VEG | proliferation CRISPR screen | Homo sapiens glutamatergic neuron, 14 days post differentiation genetically modified (CRISPRi) using CRISPR, (insertion) using CRISPR, (insertion) using TALEN inserting M. musculus Neurog2 | Yin Shen, UCSF | released |