Summary for ENCSR009KPS

Summary

Status
released
Description
Functional characterization series for the gene target HDAC6.
Donor diversity
single
Assay
Flow-FISH CRISPR screen
Biosample summary
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for chrX:48397929-49657009
Diseases
Not reported
Treatments
doxycycline
Elements references
Tiling modality
peak tiling

Attribution

ENCODE4 project
Lab
Pardis Sabeti, Broad
Award
UM1HG009435 (Pardis Sabeti, Broad)
Project
ENCODE
Aliases
pardis-sabeti:HDAC6_series_GATA
External resources
None submitted

Experiments in ENCSR009KPS

Experiments
2 experiments
Accession
Assay
Examined loci
Biosample summary
Lab
Status
Cart
ENCSR169ALPFlow-FISH CRISPR screenHDAC6 (90-100%)Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for chrX:48397929-49657009Pardis Sabeti, Broad
released
ENCSR808JNJFlow-FISH CRISPR screenHDAC6 (0-10%)Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for chrX:48397929-49657009Pardis Sabeti, Broad
released
Control experiments
2 control experiments
Accession
Control type
Biosample summary
Lab
Status
Cart
ENCSR925GGJcontrolHomo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for chrX:48397929-49657009Pardis Sabeti, Broad
released
ENCSR449TVFcontrolPardis Sabeti, Broad
released