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Summary for ENCSR009KPS

Summary

Status
released
Description
Functional characterization series for the gene target HDAC6.
Donor diversity
single
Assay
Flow-FISH CRISPR screen
Biosample summary
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for chrX:48397929-49657009
Diseases
Not reported
Treatments
doxycycline
Elements references
Tiling modality
peak tiling

Attribution

ENCODE4 project
Lab
Pardis Sabeti, Broad
Award
UM1HG009435 (Pardis Sabeti, Broad)
Project
ENCODE
Aliases
pardis-sabeti:HDAC6_series_GATA
External resources
None submitted

Experiments in ENCSR009KPS

Experiments
2 experiments
Accession
Assay
Examined loci
Biosample summary
Lab
Status
Cart
ENCSR169ALPFlow-FISH CRISPR screenHDAC6 (90-100%)Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for chrX:48397929-49657009Pardis Sabeti, Broad
released
ENCSR808JNJFlow-FISH CRISPR screenHDAC6 (0-10%)Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for chrX:48397929-49657009Pardis Sabeti, Broad
released
Control experiments
2 control experiments
Accession
Control type
Biosample summary
Lab
Status
Cart
ENCSR925GGJcontrolHomo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for chrX:48397929-49657009Pardis Sabeti, Broad
released
ENCSR449TVFcontrolPardis Sabeti, Broad
released

Files

Filter files

File format
Output type
Replicates
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Displaying 4 of 4 files

Lab custom GRCh38 (ENCAN370VJZ) processed data
(4 Files)   

Accession
File type
Output type
Genome assembly
Date added
File size
File status
ENCFF632PQY
bed CRISPR element quantificationselement quantificationsGRCh382021-05-13200 B
released
ENCFF514PCW
bigWigperturbation signalGRCh382021-05-13299 kB
released
ENCFF607OIW
bigWigperturbation signalGRCh382021-05-13284 kB
released
ENCFF845MNY
bigInteractelement gene interactions signalGRCh382021-05-1320.6 kB
released