- Description
- A ChIP-seq peak calling algorithm, implemented as an R package, that accounts for the offset in forward-strand and reverse-strand reads to improve resolution, compares enrichment in signal to background or control experiments, and can also estimate whether the available number of reads is sufficient to achieve saturation, meaning that additional reads would not allow identification of additional peaks. SPP will be used in the ENCODE 3 uniform peak calling pipeline.
- Software type
- peak caller
- Used for
- ChIP-seq, DNase-seq