Summary for ENCSR449NJV
Summary
- Status
- released
- Description
- Functional characterization series for the gene target HBG1.
- Donor diversity
- single
- Assay
- Flow-FISH CRISPR screen
- Biosample summary
- Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
- Diseases
- Not reported
- Treatments
- doxycycline
- Elements references
- ENCSR827WZZ (GRCh38 chr6:134253818-136927606, GRCh38 chr11:4091879-6419323)
- Tiling modality
- full tiling
Attribution
ENCODE4 project
- Lab
- Pardis Sabeti, Broad
- Award
- UM1HG009435 (Pardis Sabeti, Broad)
- Project
- ENCODE
- Aliases
- pardis-sabeti:HBG1_series_HEME
- External resources
- None submitted
Experiments in ENCSR449NJV
Experiments
2 experiments
Accession | Assay | Examined loci | Biosample summary | Lab | Status | Cart |
|---|---|---|---|---|---|---|
| ENCSR103FXA | Flow-FISH CRISPR screen | HBG1 (90-100%) | Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci | Pardis Sabeti, Broad | released | |
| ENCSR897GNT | Flow-FISH CRISPR screen | HBG1 (0-10%) | Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci | Pardis Sabeti, Broad | released |
Control experiments
2 control experiments
Accession | Control type | Biosample summary | Lab | Status | Cart |
|---|---|---|---|---|---|
| ENCSR692ZUM | control | Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci | Pardis Sabeti, Broad | released | |
| ENCSR206MVL | control | Pardis Sabeti, Broad | released |