{
"documents": [],
"date_created": "2016-04-19T04:19:39.922563+00:00",
"submitted_by": "/users/ef309f6b-c671-44c8-a33d-3850bd14fe63/",
"status": "released",
"lab": "/labs/job-dekker/",
"award": "/awards/U54HG007010/",
"aliases": [],
"accession": "ENCLB215KZO",
"schema_version": "20",
"alternate_accessions": [],
"spikeins_used": [],
"barcode_details": [],
"biosample": {
"accession": "ENCBS366AET",
"url": "http://www.atcc.org/ATCCAdvancedCatalogSearch/ProductDetails/tabid/452/Default.aspx?ATCCNum=HTB-10&Template=cellBiology",
"aliases": [
"john-stamatoyannopoulos:DS14413"
],
"schema_version": "26",
"status": "released",
"lab": "/labs/john-stamatoyannopoulos/",
"award": "/awards/U54HG004592/",
"date_created": "2013-12-06T21:15:10.230412+00:00",
"submitted_by": "/users/073079fd-d589-4663-9fd4-3d488208d075/",
"documents": [
"/documents/cb2278a8-7934-47f0-935e-9cc4b59e18b4/"
],
"references": [],
"source": "/sources/atcc/",
"product_id": "HTB-10",
"biosample_ontology": {
"schema_version": "1",
"references": [],
"term_id": "EFO:0002860",
"status": "released",
"classification": "cell line",
"term_name": "SK-N-MC",
"aliases": [],
"dbxrefs": [
"Cellosaurus:CVCL_0530"
],
"@id": "/biosample-types/cell_line_EFO_0002860/",
"@type": [
"BiosampleType",
"Item"
],
"uuid": "4f787e3d-719d-46be-b57b-e8791441323d",
"name": "cell_line_EFO_0002860",
"organ_slims": [
"brain",
"epithelium"
],
"cell_slims": [
"epithelial cell",
"cancer cell"
],
"developmental_slims": [
"ectoderm"
],
"system_slims": [
"central nervous system"
],
"synonyms": [
"SKNMc"
]
},
"genetic_modifications": [],
"alternate_accessions": [],
"description": "Please note: This cell line was previously described as a neuroepithelioma (ATCC HTB-10). However recent evidence reveals it is Ewing's Sarcoma (http://www.ncbi.nlm.nih.gov/pubmed/15548687, http://www.ncbi.nlm.nih.gov/biosample/3151999,http://www.ncbi.nlm.nih.gov/pubmed/25453903)",
"treatments": [],
"dbxrefs": [
"UCSC-ENCODE-cv:SK-N-MC",
"GEO:SAMN07790950"
],
"donor": {
"schema_version": "13",
"accession": "ENCDO000ABC",
"aliases": [
"encode:donor of SK-N-MC"
],
"status": "released",
"lab": "/labs/encode-consortium/",
"award": "/awards/U41HG006992/",
"date_created": "2013-12-06T21:06:23.819044+00:00",
"submitted_by": "/users/3787a0ac-f13a-40fc-a524-69628b04cd59/",
"notes": "Donor of SK-N-MC. Neuroepithelioma cell line derived from a metastatic supra-orbital human brain tumor, SK-N-MC was isolated in September of l971 and was found to have moderate dopamine - beta - hydroxylase activity as well as formaldehyde induced fluorescence indicative of intracellular catecholamines. - ATCC. (Biedler, et al. Morphology and Growth, Tumorigenicity, and Cytogenetics of Human Neuroblastoma Cells in Continuous Culture. Cancer Research 33, 2643-2652, November 1973.) The ethnicity of this donor has been updated to European as the term Caucasian is deprecated.",
"documents": [],
"references": [
"/publications/4c32f1d1-5aee-4dab-a2db-749f6e4d43cc/",
"/publications/aa642733-7a0d-44f9-a1b0-465cd833f879/"
],
"external_ids": [],
"alternate_accessions": [],
"organism": {
"schema_version": "6",
"scientific_name": "Homo sapiens",
"name": "human",
"status": "released",
"taxon_id": "9606",
"@id": "/organisms/human/",
"@type": [
"Organism",
"Item"
],
"uuid": "7745b647-ff15-4ff3-9ced-b897d4e2983c"
},
"sex": "female",
"life_stage": "child",
"age": "14",
"age_units": "year",
"health_status": "Ewing's sarcoma",
"ethnicity": [
"European"
],
"parents": [],
"siblings": [],
"dbxrefs": [
"GEO:SAMN06464587"
],
"@id": "/human-donors/ENCDO000ABC/",
"@type": [
"HumanDonor",
"Donor",
"Item"
],
"uuid": "3713e97d-f027-401f-9844-a33f2f1f58d8",
"characterizations": [],
"children": [],
"superseded_by": []
},
"organism": "/organisms/human/",
"internal_tags": [],
"@id": "/biosamples/ENCBS366AET/",
"@type": [
"Biosample",
"Item"
],
"uuid": "de16e3b3-0e3c-450c-992b-5eba7a3314ab",
"sex": "female",
"age": "14",
"age_units": "year",
"health_status": "Ewing's sarcoma",
"life_stage": "child",
"applied_modifications": [],
"characterizations": [],
"parent_of": [],
"age_display": "14 years",
"origin_batch": "/biosamples/ENCBS366AET/",
"perturbed": false,
"simple_summary": "",
"summary": "Homo sapiens SK-N-MC cell line"
},
"nucleic_acid_term_name": "DNA",
"dbxrefs": [
"GEO:GSM2828694"
],
"fragmentation_methods": [
"chemical (HindIII restriction)"
],
"treatments": [],
"hic_construction": "in situ",
"@id": "/libraries/ENCLB215KZO/",
"@type": [
"Library",
"Item"
],
"uuid": "32fb9768-067c-472a-abb2-25e02e6ca24e",
"nucleic_acid_term_id": "SO:0000352",
"@context": "/terms/",
"audit": {}
}