ENCBS873CMF / cell line
Summary
- Status
- released
- Term name
- SK-N-SH
- Term ID
- EFO:0003072
- Summary
- Homo sapiens SK-N-SH cell line genetically modified (insertion) using CRISPR targeting H. sapiens ARNTL treated with 6 μM all-trans-retinoic acid for 48 hours
- Description
- SK-N-SH cell line (treated with 6 μM all-trans-retinoic acid for 48 hours) stably expressing a C-terminal LAP-tag containing eGFP, fused to ARNTL.
Attribution
ENCODE4 project
- Lab
- Michael Snyder, Stanford
- Award PI
- Michael Snyder, Stanford
- Submitted by
- Nathaniel Watson
- Source
- Michael Snyder
- Project
- ENCODE
- External resources
- Aliases
- michael-snyder:SK-N-SH_RA_eGFP-ARNTL_CRISPR_ChIP_B1_B2_input
Treatment details
- Treatment
- 6 μM all-trans-retinoic acid (CHEBI:15367) for 48 hours
- Type
- chemical
- Purpose
- activation
Pooled from biosamples
2 biosamples
Accession | Type | Term | Summary |
|---|---|---|---|
| ENCBS813UGC | cell line | SK-N-SH | Homo sapiens SK-N-SH cell line genetically modified (insertion) using CRISPR targeting H. sapiens ARNTL treated with 6 μM all-trans-retinoic acid for 48 hours |
| ENCBS992OPI | cell line | SK-N-SH | Homo sapiens SK-N-SH cell line genetically modified (insertion) using CRISPR targeting H. sapiens ARNTL treated with 6 μM all-trans-retinoic acid for 48 hours |
Genetic modifications
Accession | Category | Purpose | Method | Nucleic acid delivery method | Site |
|---|---|---|---|---|---|
| ENCGM093MVP | insertion | tagging | CRISPR |
|
Donor information
- Status
- released
- Accession
- ENCDO000ABD
- Aliases
- encode:donor of SK-N-SH, bradley-bernstein:Donor of SK-N-SH cells, encode:donor of SH-SY5Y
- Species
- Homo sapiens
- Life stage
- child
- Age
- 4 years
- Sex
- female
- Health status
- Metastatic neuroblastoma from bone marrow
- External resources
- References