ENCAB000AEU
Antibody against Homo sapiens CREBBP
Homo sapiens
at least one cell type or tissue
awaiting characterization
- Status
- released
- Source (vendor)
- Santa Cruz Biotech
- Product ID
- sc-369
- Lot ID
- unknown
- Characterized targets
- CREBBP (Homo sapiens)
- Host
- rabbit
- Clonality
- polyclonal
- Purification
- Protein A/G
- Antigen description
- Epitope mapping at the N-terminus of CBP of human origin.
- External resources
Characterizations
CREBBP (Homo sapiens)
Method: ChIP-seq comparison
not reviewed
- Caption
- CBP ChIP-Seq analysis supports successful ChIP. A 11% of MACS-called CBP ChIP-Seq peaks (p-value < 1e-10) are found within 1000bp of a known TSS. B CBP peaks preferentially overlap with ATF2 peaks (84% within 1000bp) and to a lesser degree with ATF1, CREB, FOS, JUN and MAX transcription factors (30-50% within 1000bp). C De novo motif discovery with the MEME suite of analysis software using 100bp of sequence flanking the top 1000 CBP peaks identifies multiple canonical DNA binding motifs including GATA, TRE, STAT, C/EBP, AP-4 and RUNX1 motifs. The identification of several motifs reflects the recruitment of CBP by a number of transcription factors.
- Submitted by
- Kevin Struhl
- Lab
- Michael Snyder, Stanford
- Grant
- U54HG004558
CREBBP (Homo sapiens)
Method: immunoblot
not reviewed
- Submitted by
- Kevin Struhl
- Lab
- Michael Snyder, Stanford
- Grant
- U54HG004558