American Society of Human Genetics 2015 Annual Meeting

Members of the ENCODE consortium were at the American Society of Human Genetics' 2015 Annual Meeting from October 6th to 10th in Baltimore, Maryland, presenting the Advanced Workshop on Integrative Analysis using ENCODE and Roadmap Epigenomics DataThis workshop began with brief overviews of the ENCODE and Roadmap Epigenomics projects. Hands-on tutorials were provided regarding how to perform integrative analysis with a variety of data sets as seen in recent ENCODE and Roadmap Epigenomics publications, with a special focus on how they can be used to improve the annotation of genetic variants underlying disease.

Workshop attendees received hands-on experience using the following resources:

  • Searching for datasets using the ENCODE portal (
  • Browsing and downloading Encyclopedia annotations from ENCODE and REMC
  • Using RegulomeDB and HaploReg to query ENCODE and REMC data
  • Using the ENCODE element browser and 3D Genome Browser
  • Using ChromHMM to predict regulatory states in the genome

This workshop educated researchers, clinicians, and genetic counselors on how to use ENCODE data to generate hypotheses for further biological investigation.

For questions or more information contact:
Michael Pazin, Ph.D.

The presentations from this workshop can be found below in PDF format. All video links lead to the GenomeTV YouTube channel.

Tutorials and Presentations

   Saturday, October 10, 2015


Presentation Video Link



Additional materials

1 Workshop Introduction Feng Yue Pennsylvania State University  
2 A Brief Tour of ENCODE Mike Pazin NHGRI  Slides

The NIH Roadmap Epigenomics Program

Kim McAllister

National Institute of Environmental Health Sciences



ENCODE Standards, Data and Access

J. Michael Cherry

Stanford University


5 The ENCODE Encyclopedia and Vaiant Annotation Using RegulomeDB and HaploReg Jill Moore University of Massachusetts Medical School   Slides


ENCODE Element Browser

Yanli Wang

Pennsylvania State University



ChromHMM Tutorial 

Jason Ernst

University of California, Los Angeles


8 Concluding Remarks Manolis Kellis Massachusetts Institute of Technology