- Description
- Produces normalized genome-wide signal coverage tracks from raw read alignment files. Allows pooling of replicate datasets while allowing for replicate and data-type specific read shifting and smoothing parameters. It can be used to generate signal density maps for ChIP-seq, DNase-seq, FAIRE-seq and MNase-seq data. Wiggler also implicitly models variability in mappability to appropriately normalize signal density and distinguish missing data from true zero signal.
- Used for
- DNase-seq, ChIP-seq