- Description
- WASP is a software package for two related tasks: (1) correcting allelic bias in mapped sequencing reads and, (2) identifying molecular quantitative trait loci (QTLs) using next-generation sequencing data (e.g. gene expression QTLs or histone mark QTLs). The WASP mapper works with any read mapping pipeline that outputs BAM or SAM format. WASP identifies molecular QTLs using a statistical test that combines information about the total depth and allelic imbalance of mapped reads. WASP can call QTLs with very small sample sizes (as few as 10) compared to traditional QTL mapping approaches.
- Software type
- aligner, variant annotation
- Used for
- ChIP-seq, variant analysis, RNA-seq