- Description
- A database that uncovers the molecular basis of TF binding in the human genome based on regulatory motif analysis of all Transcription Factors (TFs) grouped by family. This allows browsing of all known motifs for each factor, curated from TRANSFAC, Jaspar, and Protein Binding Microarray (PBM) experiments, and their enrichment and instances within corresponding TF binding experiments. It also provides a list of novel regulatory motifs discovered by systematic application of several motif discovery tools (including MEME, MDscan, Weeder, AlignACE) and evaluated based on their enrichment relative to control motifs within TF-bound regions. ENCODE-motifs also provides a genome-wide map of regulatory motif instances in the human genome for both known and novel motifs.
- Software type
- database
- Used for
- community resource