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  • MPRA in WTC11
    Elements cloned into the lentiMPRA vector upstream of a minimal promoter, with barcode located in the 5' UTR of the reporter. Elements test neuronal enhancers and promoters.
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR548AQS
    released
  • CRISPRi FACS screen in activated CD4-positive, CD25-positive, alpha-beta regulatory T cell with fluorescence activated cell sorting readout of Tnfrsf18
    Mus musculus strain Rosa26-LSL-dCas9-KRAB activated CD4-positive, CD25-positive, alpha-beta regulatory T cell genetically modified (CRISPRi) using CRISPR
    Elements selection method: accessible genome regions
    Tiling modality: peak tiling
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR202QXN
    released
  • CRISPRi screen in WTC11
    WTC11 cell line genetically modified (insertion) using transduction, genetically modified (CRISPRi) using CRISPR
    Assays: CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Series
    ENCSR499VAT
    released
  • proliferation CRISPR screen in DNA cloning sample
    Functional characterization series for tiling CRIPSRi proliferation screens at genome-wide cCREs essential for neuronal differentiation
    Assays: proliferation CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Elements selection method: accessible genome regions, histone modifications, essential genes
    Series
    ENCSR737MRW
    released
  • MPRA in SK-N-SH
    Homo sapiens SK-N-SH, 24 hours post-nucleic acid delivery time genetically modified (episome) using transient transfection
    Lab: Ryan Tewhey, JAX
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR959NUX
    released
  • MPRA in HepG2
    Homo sapiens HepG2, 24 hours post-nucleic acid delivery time genetically modified (episome) using transient transfection
    Lab: Ryan Tewhey, JAX
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR167HAR
    released
  • MPRA in K562
    Homo sapiens K562, 24 hours post-nucleic acid delivery time genetically modified (episome) using transient transfection
    Lab: Ryan Tewhey, JAX
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR341GVP
    released
  • MPRA in HepG2
    Homo sapiens HepG2, 24 hours post-nucleic acid delivery time genetically modified (episome) using transient transfection
    Lab: Ryan Tewhey, JAX
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR694VUM
    released
  • MPRA in K562
    Homo sapiens K562, 24 hours post-nucleic acid delivery time genetically modified (episome) using transient transfection
    Lab: Ryan Tewhey, JAX
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR909JVP
    released
  • MPRA in K562
    Homo sapiens K562, 24 hours post-nucleic acid delivery time genetically modified (episome) using transient transfection
    Lab: Ryan Tewhey, JAX
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR820RPI
    released
  • MPRA in WTC11
    Elements cloned into the lentiMPRA vector upstream of a minimal promoter, with barcode located in the 5' UTR of the reporter. Elements test potential HepG2, K562, and WTC11 enhancers and promoters of all protein-coding genes.
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR336MKI
    released
  • MPRA in HepG2
    Elements cloned into the lentiMPRA vector upstream of a minimal promoter, with barcode located in the 5' UTR of the reporter. Elements test potential HepG2, K562, and WTC11 enhancers and promoters of all protein-coding genes.
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR405QCT
    released
  • MPRA in K562
    Elements cloned into the lentiMPRA vector upstream of a minimal promoter, with barcode located in the 5' UTR of the reporter. Elements test potential HepG2, K562, and WTC11 enhancers and promoters of all protein-coding genes.
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR203UFY
    released
  • MPRA in WTC11
    Elements cloned into the lentiMPRA vector upstream of a minimal promoter, with barcode located in the 5' UTR of the reporter. Elements test potential WTC11 enhancers and promoters of protein-coding genes.
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR244FWB
    released
  • STARR-seq in K562
    Homo sapiens K562 genetically modified (episome) using transient transfection
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR926NDZ
    released
  • STARR-seq in glutamatergic neuron
    Homo sapiens glutamatergic neuron, 7 days post differentiation genetically modified (episome) using transient transfection, (insertion) using TALEN inserting M. musculus Neurog2
    Lab: Kevin White, UChicago
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR258QGF
    released
  • perturbation followed by snATAC-seq in K562
    K562 cell line genetically modified (insertion) using transduction, genetically modified (CRISPRi) using CRISPR
    Assays: perturbation followed by snATAC-seq
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Series
    ENCSR513XAG
    released
  • CRISPR cutting screen of GATA1 locus in K562
    Homo sapiens K562 genetically modified (insertion) using transduction (low MOI), using CRISPR cutting (sgRNA) for GATA1 locus
    Assays: CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: GATA1
    Tiling modality: peak tiling
    Series
    ENCSR825HCS
    released
  • MPRA in HepG2
    Elements cloned into the lentiMPRA vector upstream of a minimal promoter, with barcode located in the 5' UTR of the reporter. Elements test HepG2 enhancers and promoters of all protein-coding genes.
    Elements selection method: synthetic elements
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR632EPR
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR164QHU
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR492UFM
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR036ESM
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR806RFP
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR781BZX
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR732NDT
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR064DGF
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR967KFJ
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR429NXH
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR237HTM
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR733ACM
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR410PBY
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR835UFV
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR990JZW
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR871IOQ
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR760YZX
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR565URQ
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR538UNX
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR437UAW
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR259RIY
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR811GPF
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR735JXB
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR863PWK
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR985PCK
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR469BIA
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR192MGG
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR939VYR
    released
  • MPRA of SHH locus in NIH3T3
    Elements cloned into the pGL4Z vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the ZRS enhancer.
    Loci: SHH
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR035ODX
    released
  • MPRA of SHH locus in NIH3T3
    Elements cloned into the pGL4Z vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the ZRS enhancer.
    Loci: SHH
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR426MVD
    released
  • MPRA of ZFAND3 locus in MIN6
    Elements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the ZFAND3 enhancer.
    Loci: ZFAND3
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR909OSG
    released
  • MPRA in Neuro-2a
    Elements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the ultra conserved element UC88.
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR642DFC
    released
  • MPRA of TERT locus in glial cell
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the TERT promoter.
    Loci: TERT
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR976YTH
    released
  • MPRA of TERT locus in glial cell
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the TERT promoter.
    Loci: TERT
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR759LCV
    released
  • MPRA of TERT locus in glial cell
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the TERT promoter.
    Loci: TERT
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR782GCT
    released
  • MPRA of TERT locus in HEK293T
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the TERT promoter.
    Loci: TERT
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR821FQH
    released
  • MPRA of TCF7L2 locus in MIN6
    Elements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the TCF7L2 enhancer.
    Loci: TCF7L2
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR981ILP
    released
  • MPRA of SORT1 locus in HepG2
    Elements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the SORT enhancer, using 3' to 5' direction.
    Loci: SORT1
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR281FRP
    released
  • MPRA of SORT1 locus in HepG2
    Elements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the SORT1 enhancer.
    Loci: SORT1
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR058RIG
    released
  • MPRA of SORT1 locus in HepG2
    Elements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the SORT1 enhancer.
    Loci: SORT1
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR259LFO
    released
  • MPRA of RET locus in Neuro-2a
    Elements cloned into the pGL3 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the RET enhancer.
    Loci: RET
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR397JKG
    released
  • MPRA of PKLR locus in K562
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the PKLR promoter.
    Loci: PKLR
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR987WTK
    released
  • MPRA of PKLR locus in K562
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the PKLR promoter.
    Loci: PKLR
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR845WND
    released
  • MPRA of MYC locus in HEK293T
    Elements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the MYC enhancer around SNP rs6983267.
    Loci: MYC
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR883DOL
    released
  • MPRA of MYC locus in LNCAP
    Elements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the MYC enhancer around SNP rs11986220.
    Loci: MYC
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR812ICI
    released
  • MPRA of MSMB locus in HEK293T
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the MSMB promoter.
    Loci: MSMB
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR934HHR
    released
  • MPRA of LDLR locus in HepG2
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the LDLR promoter.
    Loci: LDLR
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR739VGY
    released
  • MPRA of LDLR locus in HepG2
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the LDLR promoter.
    Loci: LDLR
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR912KDN
    released
  • MPRA of IRF6 locus in HaCaT
    Elements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the IRF6 enhancer.
    Loci: IRF6
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR270PHO
    released
  • MPRA of IRF4 locus in SK-MEL-28
    Elements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the IRF4 enhancer.
    Loci: IRF4
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR006GAG
    released
  • MPRA of HNF4A locus in HEK293T
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the HNF4A promoter.
    Loci: HNF4A
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR701WDZ
    released
  • MPRA of HBG1 locus in HEL
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the HBG1 promoter.
    Loci: HBG1
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR686LKF
    released
  • MPRA of HBB locus in HEL
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the HBB promoter.
    Loci: HBB
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR200LXA
    released
  • MPRA of GP1BB locus in HEL
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the GP1BB promoter.
    Loci: GP1BB
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR436DRI
    released
  • MPRA of FOXE1 locus in HeLa
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the FOXE1 promoter.
    Loci: FOXE1
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR373WOB
    released
  • MPRA of F9 locus in HepG2
    Elements cloned into the pGL4.11 vector upstream of the reporter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the F9 promoter.
    Loci: F9
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR352YKN
    released
  • MPRA of BCL11A locus in HEL
    Elements cloned into the pGL4.23 vector upstream of a minimal promoter, with barcode located in the 3' UTR of the reporter. Elementas are generated by error-prone PCR of the BCL11A enhancer.
    Loci: BCL11A
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR330ZFH
    released
  • CRISPR cutting FACS screen of Sox2 locus in F123 with endogenous protein Sort-seq readout of Sox2
    Mus musculus F123 genetically modified (insertion) using transduction, using CRISPR cutting (sgRNA) for Sox2 locus
    Assays: FACS CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: Sox2
    Tiling modality: full tiling
    Series
    ENCSR048THP
    released
  • CRISPR cutting FACS screen of Esrrb locus in F123 with endogenous protein Sort-seq readout of Esrrb
    Mus musculus F123 genetically modified (insertion) using transduction, using CRISPR cutting (sgRNA) for Esrrb locus
    Assays: FACS CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: Esrrb
    Tiling modality: full tiling
    Series
    ENCSR377JZI
    released
  • CRISPR cutting FACS screen of Dppa2 locus in F123 with endogenous protein Sort-seq readout of Dppa2
    Mus musculus F123 genetically modified (insertion) using transduction, using CRISPR cutting (sgRNA) for Dppa2 locus
    Assays: FACS CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: Dppa2
    Tiling modality: full tiling
    Series
    ENCSR961ANR
    released
  • MPRA in DNA cloning sample
    These MPRA datasets test a mix of short, medium, and long elements cloned into the pGL4 vector upstream of a minimal promoter.
    Assays: MPRA
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Series
    ENCSR643SGO
    released
  • MPRA in DNA cloning sample
    These MPRA datasets test the same set of elements cloned into the pGL4 vector upstream of a minimal promoter in both the forward and reverse orientations in parallel.
    Assays: MPRA
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Series
    ENCSR473OOU
    released
  • MPRA in DNA cloning sample
    These MPRA datasets screen a library of 2,440 candidate liver enhancers and controls for regulatory activity in HepG2 cells using nine different MPRA designs.
    Assays: MPRA
    Lab: Nadav Ahituv, UCSF
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Series
    ENCSR033VBW
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR457ELJ
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR144DER
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR736PQO
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR600ZYN
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR913MGM
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR324OMB
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR845UQL
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR473XKW
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR714ZPV
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR069LMA
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR558ONA
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR142LCJ
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR530VJU
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR596GRS
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR013RKR
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR317JEF
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR234KYQ
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR641TMZ
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR778BOC
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR084SMR
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR237FIT
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR455RKY
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR115WVX
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR554DKZ
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR392SOG
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR530FAY
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR575JNK
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR850UDY
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR764JRO
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR759PFN
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR824ULT
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR217IPV
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR978EJW
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR075LRH
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR611GNK
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR327HGD
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR228SSJ
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR054RJA
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR651XKB
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR831DYO
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR152MFW
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR687LJN
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR451IZO
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR462ZUY
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR244IQF
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR982BVU
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR521TJO
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR987OXC
    released
  • enhancer reporter assay in whole organism
    strain FVB/NCrl whole organism embryo (11.5 days) genetically modified (insertion) using mouse pronuclear microinjection
    Lab: Len Pennacchio, LBNL
    Project: ENCODE
    Transgenic Enhancer Experiment
    ENCSR861JQO
    released
  • CRISPRi proliferation screen of multiple loci in WTC11
    Homo sapiens WTC11 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Elements selection method: accessible genome regions
    Tiling modality: peak tiling
    Series
    ENCSR534RBC
    released
  • CRISPR cutting proliferation screen of multiple loci in WTC11
    Homo sapiens WTC11 genetically modified (insertion) using transduction, using CRISPR cutting (sgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Elements selection method: accessible genome regions
    Tiling modality: peak tiling
    Series
    ENCSR499GLI
    released
  • CRISPRi proliferation screen of multiple loci in PC-3
    Homo sapiens PC-3 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: MYC, MYB
    Tiling modality: full tiling
    Series
    ENCSR703YMV
    released
  • CRISPRi proliferation screen of multiple loci in DU 145
    Homo sapiens DU 145 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: MYC, MYB
    Tiling modality: full tiling
    Series
    ENCSR112MYY
    released
  • CRISPRi proliferation screen of multiple loci in NCI-H460
    Homo sapiens NCI-H460 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: MYC, MYB
    Tiling modality: full tiling
    Series
    ENCSR401HFH
    released
  • CRISPRi proliferation screen of multiple loci in A549
    Homo sapiens A549 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: MYC, MYB
    Tiling modality: full tiling
    Series
    ENCSR917YQW
    released
  • CRISPRi proliferation screen of multiple loci in MDA-MB-231
    Homo sapiens MDA-MB-231 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: MYC, MYB
    Tiling modality: full tiling
    Series
    ENCSR371XHF
    released
  • CRISPRi proliferation screen of multiple loci in MCF-7
    Homo sapiens MCF-7 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: MYC, MYB
    Tiling modality: full tiling
    Series
    ENCSR147TRG
    released
  • CRISPRi proliferation screen of multiple loci in HepG2
    Homo sapiens HepG2 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: MYC, MYB
    Tiling modality: full tiling
    Series
    ENCSR319WEU
    released
  • CRISPRi proliferation screen of multiple loci in SW620
    Homo sapiens SW620 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: MYC, MYB
    Tiling modality: full tiling
    Series
    ENCSR172TKR
    released
  • CRISPRi proliferation screen of multiple loci in HCT116
    Homo sapiens HCT116 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: MYC, MYB
    Tiling modality: full tiling
    Series
    ENCSR675XBE
    released
  • CRISPRi proliferation screen of multiple loci in K562
    Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: MYC, MYB
    Tiling modality: full tiling
    Series
    ENCSR411TAL
    released
  • MPRA in K562
    Homo sapiens K562, 24 hours post-nucleic acid delivery time genetically modified (episome) using transient transfection
    Elements selection method: sequence variants
    Lab: Ryan Tewhey, JAX
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR971PLA
    released
  • CRISPRi proliferation screen in OCI-AML2
    Functional characterization series of CRISPRi (dCas9-KRAB) growth screen targeting putative essential DHSs in K562. (validation screen in OCI-AML2).
    Assays: proliferation CRISPR screen
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Tiling modality: sparse peak
    Series
    ENCSR179FSH
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series of CRISPRi (dCas9-KRAB) growth screen targeting putative essential DHSs in K562 .(validation screen in K562).
    Assays: proliferation CRISPR screen
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Tiling modality: sparse peak
    Series
    ENCSR274OEB
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series of CRISPRi (dCas9-KRAB) growth screen targeting all previously identified open chromatin regions (DHSs) in K562. (Discovery screen).
    Assays: proliferation CRISPR screen
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Tiling modality: peak tiling
    Series
    ENCSR690DTG
    released
  • CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of HBS1L
    Functional characterization series for the gene target HBS1L.
    Assays: Flow-FISH CRISPR screen
    Lab: Pardis Sabeti, Broad
    Project: ENCODE
    Tiling modality: full tiling
    Series
    ENCSR759RSA
    released
  • CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of MYB
    Functional characterization series for the gene target MYB.
    Assays: Flow-FISH CRISPR screen
    Lab: Pardis Sabeti, Broad
    Project: ENCODE
    Tiling modality: full tiling
    Series
    ENCSR408VHJ
    released
  • CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of HBE1
    Functional characterization series for the gene target HBE1.
    Assays: Flow-FISH CRISPR screen
    Lab: Pardis Sabeti, Broad
    Project: ENCODE
    Tiling modality: full tiling
    Series
    ENCSR564EPW
    released
  • CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of HBG2
    Functional characterization series for the gene target HBG2.
    Assays: Flow-FISH CRISPR screen
    Lab: Pardis Sabeti, Broad
    Project: ENCODE
    Tiling modality: full tiling
    Series
    ENCSR459QNY
    released
  • CRISPRi Flow-FISH screen in K562 with HCR-FlowFISH readout of HBG1
    Functional characterization series for the gene target HBG1.
    Assays: Flow-FISH CRISPR screen
    Lab: Pardis Sabeti, Broad
    Project: ENCODE
    Tiling modality: full tiling
    Series
    ENCSR449NJV
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for CRISPRi/dCas9-RYBP sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: sparse peak
    Series
    ENCSR369UFO
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for CRISPRi/dCas9-KRAB-WSR7EEE sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: sparse peak
    Series
    ENCSR386FFV
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for CRISPRi/dCas9-KRAB-MGA1-MGA2 sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: sparse peak
    Series
    ENCSR427OCU
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for dCas9-ZNF705-KRAB/CRISPRi tiling proliferation screens at a subset of cCREs around essential genes
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: peak tiling
    Series
    ENCSR372CKT
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for dCas9-RYBP/CRISPRi tiling proliferation screens at a subset of cCREs around essential genes
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: peak tiling
    Series
    ENCSR381RDB
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for dCas9-KRAB-WSR7EEE/CRISPRi tiling proliferation screens at a subset of cCREs around essential genes
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: peak tiling
    Series
    ENCSR295VER
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for dCas9-KRAB/CRISPRi tiling proliferation screens at a subset of cCREs around essential genes
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: peak tiling
    Series
    ENCSR446RYW
    released
  • CRISPR dCas proliferation screen in K562
    Functional characterization series for dCas9 tiling proliferation screens at a subset of cCREs around essential genes
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: peak tiling
    Series
    ENCSR997ZOY
    released
  • CRISPR cutting proliferation screen of CTCF locus in K562
    Functional characterization series for Cas9/CRISPR fine-mapping proliferation screens at hit and non-hit CTCF motifs in loop anchors (and their partner anchors) from the CTCF growth screen
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: TF binding sites
    Loci: CTCF
    Tiling modality: peak tiling
    Series
    ENCSR246NKQ
    released
  • CRISPR dCas proliferation screen of CTCF locus in K562
    Functional characterization series for dCas9/CRISPRd proliferation screens at CTCF motifs in loop anchors
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: TF binding sites
    Loci: CTCF
    Tiling modality: sparse peak
    Series
    ENCSR106NZI
    released
  • CRISPRa proliferation screen of CTCF locus in K562
    Functional characterization series for dCas9-VPR/CRISPRa proliferation screens at CTCF motifs in loop anchors
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: TF binding sites
    Loci: CTCF
    Tiling modality: sparse peak
    Series
    ENCSR995PKT
    released
  • CRISPR cutting proliferation screen of CTCF locus in K562
    Functional characterization series for Cas9/CRISPRk proliferation screens at CTCF motifs in loop anchors
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: TF binding sites
    Loci: CTCF
    Tiling modality: sparse peak
    Series
    ENCSR022LUE
    released
  • CRISPRi proliferation screen of CTCF locus in K562
    Functional characterization series for dCas9-KRAB/CRISPRi proliferation screens at CTCF motifs in loop anchors
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: TF binding sites
    Loci: CTCF
    Tiling modality: sparse peak
    Series
    ENCSR127CQV
    released
  • STARR-seq in K562
    Homo sapiens K562 genetically modified (episome) using transient transfection
    Elements selection method: accessible genome regions
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR312UQM
    released
  • STARR-seq in activated T-helper 17 cell
    Mus musculus strain C57BL/6NJ activated T-helper 17 cell genetically modified (episome) using transient transfection
    Elements selection method: accessible genome regions
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR417EQC
    released
  • STARR-seq in glutamatergic neuron
    Homo sapiens glutamatergic neuron, 14 days post differentiation genetically modified (episome) using transient transfection, (insertion) using TALEN inserting M. musculus Neurog2 originated from WTC11
    Lab: Kevin White, UChicago
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR433JKU
    released
  • STARR-seq in WTC11
    Homo sapiens WTC11 genetically modified (episome) using transient transfection, (insertion) using TALEN inserting M. musculus Neurog2
    Lab: Kevin White, UChicago
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR749AQU
    released
  • STARR-seq in activated CD4-positive, CD25-positive, alpha-beta regulatory T cell
    Mus musculus strain C57BL/6NJ activated CD4-positive, CD25-positive, alpha-beta regulatory T cell genetically modified (episome) using transient transfection
    Elements selection method: accessible genome regions
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR763SPB
    released
  • STARR-seq in activated T-helper 17 cell
    Mus musculus strain C57BL/6NJ activated T-helper 17 cell genetically modified (episome) using transient transfection
    Elements selection method: accessible genome regions
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR576KQE
    released
  • STARR-seq in activated T-helper 2 cell
    Mus musculus strain C57BL/6NJ activated T-helper 2 cell genetically modified (episome) using transient transfection
    Elements selection method: accessible genome regions
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR300TTB
    released
  • STARR-seq in activated T-helper 1 cell
    Mus musculus strain C57BL/6NJ activated T-helper 1 cell genetically modified (episome) using transient transfection
    Elements selection method: accessible genome regions
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR945FEC
    released
  • STARR-seq in activated naive CD4-positive, alpha-beta T cell
    Mus musculus strain C57BL/6NJ activated naive CD4-positive, alpha-beta T cell genetically modified (episome) using transient transfection
    Elements selection method: accessible genome regions
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR744ZON
    released
  • CRISPR dCas proliferation screen of multiple loci in K562
    Functional characterization series for tiling, dCas9/CRISPRd proliferation screens at the GATA1 locus
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Loci: GATA1, MYB, ZMYND8
    Tiling modality: full tiling
    Series
    ENCSR534GZO
    released
  • CRISPRa proliferation screen of multiple loci in K562
    Functional characterization series for tiling, dCas9-VPR/CRISPRa proliferation screens at the GATA1 locus
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Loci: GATA1, MYB, ZMYND8
    Tiling modality: full tiling
    Series
    ENCSR882EWB
    released
  • CRISPR cutting proliferation screen of multiple loci in K562
    Functional characterization series for tiling, Cas9/CRISPRk proliferation screens at the GATA1 locus
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Loci: GATA1, MYB, ZMYND8
    Tiling modality: full tiling
    Series
    ENCSR966CJN
    released
  • CRISPRi proliferation screen of multiple loci in K562
    Functional characterization series for tiling, dCas9-KRAB/CRISPRi proliferation screens at the GATA1 locus
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Loci: GATA1, MYB, ZMYND8
    Tiling modality: full tiling
    Series
    ENCSR719QWB
    released
  • CRISPR cutting proliferation screen of MYC locus in K562
    Homo sapiens K562 genetically modified (insertion) using transduction (low MOI), using CRISPR cutting (sgRNA) for MYC locus
    Assays: proliferation CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: MYC
    Tiling modality: peak tiling
    Series
    ENCSR042KBK
    released
  • CRISPR cutting proliferation screen of GATA1 locus in K562
    Homo sapiens K562 genetically modified (insertion) using transduction (low MOI), using CRISPR cutting (sgRNA) for GATA1 locus
    Assays: proliferation CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: GATA1
    Tiling modality: peak tiling
    Series
    ENCSR674CXK
    released
  • STARR-seq in pancreas organoid
    Homo sapiens organoid with pancreatic ductal adenocarcinoma; pancreas genetically modified (episome) using transient transfection
    Elements selection method: accessible genome regions, histone modifications
    Lab: Kevin White, UChicago
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR230PPM
    released
  • STARR-seq in pancreas organoid
    Homo sapiens organoid with pancreatic ductal adenocarcinoma; pancreas genetically modified (episome) using transient transfection
    Elements selection method: accessible genome regions, histone modifications, DNase hypersensitive sites
    Lab: Kevin White, UChicago
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR948LAJ
    released
  • STARR-seq in pancreas organoid
    Homo sapiens organoid with pancreatic ductal adenocarcinoma; pancreas genetically modified (episome) using transient transfection
    Elements selection method: accessible genome regions, histone modifications
    Lab: Kevin White, UChicago
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR001HGB
    released
  • STARR-seq in pancreas organoid
    Homo sapiens organoid with pancreatic ductal adenocarcinoma; pancreas genetically modified (episome) using transient transfection
    Elements selection method: accessible genome regions, histone modifications, DNase hypersensitive sites
    Lab: Kevin White, UChicago
    Project: ENCODE
    Functional Characterization Experiment
    ENCSR874TTC
    released
  • CRISPRi proliferation screen in K562
    K562 cell line genetically modified (insertion) using transduction, genetically modified (CRISPRi) using CRISPR
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Elements selection method: histone modifications
    Tiling modality: peak tiling
    Series
    ENCSR918PMD
    released
  • CRISPRi proliferation screen in HCT116
    HCT116 cell line genetically modified (insertion) using transduction, genetically modified (CRISPRi) using CRISPR
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Elements selection method: histone modifications
    Tiling modality: peak tiling
    Series
    ENCSR924MQG
    released
  • CRISPR cutting FACS screen of Sox2 locus in F123 with endogenous protein Sort-seq readout of Sox2
    Mus musculus F123 genetically modified (insertion) using CRISPR (sgRNA) targeting M. musculus Sox2, (insertion) using transduction, using CRISPR cutting (sgRNA) for Sox2 locus
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Loci: Sox2
    Tiling modality: peak tiling
    Series
    ENCSR668TVE
    released
  • CRISPR cutting FACS screen of SIN3A locus in glutamatergic neuron with endogenous protein Sort-seq readout of SIN3A
    Homo sapiens glutamatergic neuron genetically modified (insertion) using CRISPR (pgRNA) targeting H. sapiens SIN3A, (insertion) using transduction, using CRISPR cutting (pgRNA) for SIN3A locus
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: SIN3A
    Tiling modality: full tiling
    Series
    ENCSR221WBZ
    released
  • CRISPR cutting FACS screen of SIN3A locus in WTC11 with endogenous protein Sort-seq readout of SIN3A
    Homo sapiens WTC11 genetically modified (insertion) using CRISPR (pgRNA) targeting H. sapiens SIN3A, (insertion) using transduction, using CRISPR cutting (pgRNA) for SIN3A locus
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: SIN3A
    Tiling modality: full tiling
    Series
    ENCSR066VPH
    released
  • CRISPR cutting FACS screen of APP locus in glutamatergic neuron with endogenous protein Sort-seq readout of APP
    Homo sapiens glutamatergic neuron genetically modified (insertion) using CRISPR (pgRNA) targeting H. sapiens APP, (insertion) using transduction, using CRISPR cutting (pgRNA) for APP locus
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: APP
    Tiling modality: full tiling
    Series
    ENCSR760PTC
    released
  • CRISPR cutting FACS screen of SIN3A locus in glutamatergic neuron with endogenous protein Sort-seq readout of SIN3A
    Homo sapiens glutamatergic neuron genetically modified (insertion) using CRISPR (pgRNA) targeting H. sapiens SIN3A, (insertion) using transduction, using CRISPR cutting (pgRNA) for SIN3A locus
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: SIN3A
    Tiling modality: full tiling
    Series
    ENCSR544QLG
    released
  • CRISPR cutting FACS screen of Esrrb locus in F123 with endogenous protein Sort-seq readout of Esrrb
    Mus musculus F123 genetically modified (insertion) using CRISPR (sgRNA) targeting M. musculus Esrrb, (insertion) using transduction, using CRISPR cutting (sgRNA) for Esrrb locus
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Loci: Esrrb
    Tiling modality: peak tiling
    Series
    ENCSR276PFX
    released
  • CRISPR cutting FACS screen of Dppa2 locus in F123 with endogenous protein Sort-seq readout of Dppa2
    Mus musculus F123 genetically modified (insertion) using CRISPR (sgRNA) targeting M. musculus Dppa2, (insertion) using transduction, using CRISPR cutting (sgRNA) for Dppa2 locus
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Loci: Dppa2
    Tiling modality: peak tiling
    Series
    ENCSR709VRX
    released
  • CRISPR cutting FACS screen of MECP2 locus in glutamatergic neuron with endogenous protein Sort-seq readout of MECP2
    Homo sapiens glutamatergic neuron genetically modified (insertion) using CRISPR (pgRNA) targeting H. sapiens MECP2, (insertion) using transduction, using CRISPR cutting (pgRNA) for MECP2 locus
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: MECP2
    Tiling modality: full tiling
    Series
    ENCSR606RFJ
    released
  • CRISPR cutting FACS screen of FMR1 locus in glutamatergic neuron with endogenous protein Sort-seq readout of FMR1
    glutamatergic neuron in vitro differentiated cells genetically modified (insertion) using transduction, genetically modified (insertion) using CRISPR targeting H. sapiens FMR1, genetically modified (CRISPR cutting) using CRISPR for FMR1 locus,
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: FMR1
    Tiling modality: full tiling
    Series
    ENCSR884ZFA
    released
  • CRISPR cutting FACS screen of Esrrb locus in F123 with endogenous protein Sort-seq readout of Esrrb
    Mus musculus F123 genetically modified (insertion) using transduction, using CRISPR cutting (sgRNA) for Esrrb locus
    Assays: FACS CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: Esrrb
    Tiling modality: full tiling
    Series
    ENCSR673HHC
    released
  • CRISPR cutting FACS screen of APP locus in WTC11 with endogenous protein Sort-seq readout of APP
    Homo sapiens WTC11 genetically modified (insertion) using CRISPR (pgRNA) targeting H. sapiens APP, (insertion) using transduction, using CRISPR cutting (pgRNA) for APP locus
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: APP
    Tiling modality: full tiling
    Series
    ENCSR875WZX
    released
  • CRISPR cutting FACS screen of APP locus in glutamatergic neuron with endogenous protein Sort-seq readout of APP
    Homo sapiens glutamatergic neuron genetically modified (insertion) using CRISPR (pgRNA) targeting H. sapiens APP, (insertion) using transduction, using CRISPR cutting (pgRNA) for APP locus
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: APP
    Tiling modality: full tiling
    Series
    ENCSR385YAU
    released
  • CRISPR cutting FACS screen of Esrrb locus in F123 with endogenous protein Sort-seq readout of Esrrb
    Mus musculus F123 genetically modified (insertion) using CRISPR (sgRNA) targeting M. musculus Esrrb, (insertion) using transduction, using CRISPR cutting (sgRNA) for Esrrb locus
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Loci: Esrrb
    Tiling modality: peak tiling
    Series
    ENCSR680YTL
    released
  • CRISPR cutting FACS screen of Dppa2 locus in F123 with endogenous protein Sort-seq readout of Dppa2
    Mus musculus F123 genetically modified (insertion) using transduction, using CRISPR cutting (sgRNA) for Dppa2 locus
    Assays: FACS CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: Dppa2
    Tiling modality: full tiling
    Series
    ENCSR948DGU
    released
  • CRISPR cutting FACS screen of APP locus in WTC11 with endogenous protein Sort-seq readout of APP
    Homo sapiens WTC11 genetically modified (insertion) using CRISPR (pgRNA) targeting H. sapiens APP, (insertion) using transduction, using CRISPR cutting (pgRNA) for APP locus
    Assays: FACS CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: APP
    Tiling modality: full tiling
    Series
    ENCSR759NRS
    released