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  • CRISPRi proliferation screen of multiple loci in K562
    Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Loci: MYC, MYB
    Tiling modality: full tiling
    Series
    ENCSR411TAL
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series of CRISPRi (dCas9-KRAB) growth screen targeting putative essential DHSs in K562 .(validation screen in K562).
    Assays: proliferation CRISPR screen
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Tiling modality: sparse peak
    Series
    ENCSR274OEB
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series of CRISPRi (dCas9-KRAB) growth screen targeting all previously identified open chromatin regions (DHSs) in K562. (Discovery screen).
    Assays: proliferation CRISPR screen
    Lab: Tim Reddy, Duke
    Project: ENCODE
    Tiling modality: peak tiling
    Series
    ENCSR690DTG
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for CRISPRi/dCas9-RYBP sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: sparse peak
    Series
    ENCSR369UFO
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for CRISPRi/dCas9-KRAB-WSR7EEE sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: sparse peak
    Series
    ENCSR386FFV
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for CRISPRi/dCas9-KRAB-MGA1-MGA2 sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: sparse peak
    Series
    ENCSR427OCU
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for dCas9-ZNF705-KRAB/CRISPRi tiling proliferation screens at a subset of cCREs around essential genes
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: peak tiling
    Series
    ENCSR372CKT
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for dCas9-RYBP/CRISPRi tiling proliferation screens at a subset of cCREs around essential genes
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: peak tiling
    Series
    ENCSR381RDB
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for dCas9-KRAB-WSR7EEE/CRISPRi tiling proliferation screens at a subset of cCREs around essential genes
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: peak tiling
    Series
    ENCSR295VER
    released
  • CRISPRi proliferation screen in K562
    Functional characterization series for dCas9-KRAB/CRISPRi tiling proliferation screens at a subset of cCREs around essential genes
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: peak tiling
    Series
    ENCSR446RYW
    released
  • CRISPR dCas proliferation screen in K562
    Functional characterization series for dCas9 tiling proliferation screens at a subset of cCREs around essential genes
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: DNase hypersensitive sites
    Tiling modality: peak tiling
    Series
    ENCSR997ZOY
    released
  • CRISPR cutting proliferation screen of CTCF locus in K562
    Functional characterization series for Cas9/CRISPR fine-mapping proliferation screens at hit and non-hit CTCF motifs in loop anchors (and their partner anchors) from the CTCF growth screen
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: TF binding sites
    Loci: CTCF
    Tiling modality: peak tiling
    Series
    ENCSR246NKQ
    released
  • CRISPR dCas proliferation screen of CTCF locus in K562
    Functional characterization series for dCas9/CRISPRd proliferation screens at CTCF motifs in loop anchors
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: TF binding sites
    Loci: CTCF
    Tiling modality: sparse peak
    Series
    ENCSR106NZI
    released
  • CRISPRa proliferation screen of CTCF locus in K562
    Functional characterization series for dCas9-VPR/CRISPRa proliferation screens at CTCF motifs in loop anchors
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: TF binding sites
    Loci: CTCF
    Tiling modality: sparse peak
    Series
    ENCSR995PKT
    released
  • CRISPR cutting proliferation screen of CTCF locus in K562
    Functional characterization series for Cas9/CRISPRk proliferation screens at CTCF motifs in loop anchors
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: TF binding sites
    Loci: CTCF
    Tiling modality: sparse peak
    Series
    ENCSR022LUE
    released
  • CRISPRi proliferation screen of CTCF locus in K562
    Functional characterization series for dCas9-KRAB/CRISPRi proliferation screens at CTCF motifs in loop anchors
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Elements selection method: TF binding sites
    Loci: CTCF
    Tiling modality: sparse peak
    Series
    ENCSR127CQV
    released
  • CRISPR dCas proliferation screen of multiple loci in K562
    Functional characterization series for tiling, dCas9/CRISPRd proliferation screens at the GATA1 locus
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Loci: GATA1, MYB, ZMYND8
    Tiling modality: full tiling
    Series
    ENCSR534GZO
    released
  • CRISPRa proliferation screen of multiple loci in K562
    Functional characterization series for tiling, dCas9-VPR/CRISPRa proliferation screens at the GATA1 locus
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Loci: GATA1, MYB, ZMYND8
    Tiling modality: full tiling
    Series
    ENCSR882EWB
    released
  • CRISPR cutting proliferation screen of multiple loci in K562
    Functional characterization series for tiling, Cas9/CRISPRk proliferation screens at the GATA1 locus
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Loci: GATA1, MYB, ZMYND8
    Tiling modality: full tiling
    Series
    ENCSR966CJN
    released
  • CRISPRi proliferation screen of multiple loci in K562
    Functional characterization series for tiling, dCas9-KRAB/CRISPRi proliferation screens at the GATA1 locus
    Assays: proliferation CRISPR screen
    Lab: Will Greenleaf, Stanford
    Project: ENCODE
    Loci: GATA1, MYB, ZMYND8
    Tiling modality: full tiling
    Series
    ENCSR719QWB
    released
  • CRISPR cutting proliferation screen of MYC locus in K562
    Homo sapiens K562 genetically modified (insertion) using transduction (low MOI), using CRISPR cutting (sgRNA) for MYC locus
    Assays: proliferation CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: MYC
    Tiling modality: peak tiling
    Series
    ENCSR042KBK
    released
  • CRISPR cutting proliferation screen of GATA1 locus in K562
    Homo sapiens K562 genetically modified (insertion) using transduction (low MOI), using CRISPR cutting (sgRNA) for GATA1 locus
    Assays: proliferation CRISPR screen
    Lab: Yin Shen, UCSF
    Project: ENCODE
    Loci: GATA1
    Tiling modality: peak tiling
    Series
    ENCSR674CXK
    released
  • CRISPRi proliferation screen in K562
    K562 cell line genetically modified (insertion) using transduction, genetically modified (CRISPRi) using CRISPR
    Assays: proliferation CRISPR screen
    Lab: Bing Ren, UCSD
    Project: ENCODE
    Elements selection method: histone modifications
    Tiling modality: peak tiling
    Series
    ENCSR918PMD
    released