Showing 37 of 37 results
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- proliferation CRISPR screen in DNA cloning sampleFunctional characterization series for tiling CRIPSRi proliferation screens at genome-wide cCREs essential for neuronal differentiationAssays: proliferation CRISPR screenLab: Yin Shen, UCSFProject: ENCODEElements selection method: accessible genome regions, histone modifications, essential genes
- CRISPRi proliferation screen of multiple loci in WTC11Homo sapiens WTC11 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
- CRISPR cutting proliferation screen of multiple loci in WTC11Homo sapiens WTC11 genetically modified (insertion) using transduction, using CRISPR cutting (sgRNA) for multiple loci
- CRISPRi proliferation screen of multiple loci in PC-3Homo sapiens PC-3 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
- CRISPRi proliferation screen of multiple loci in DU 145Homo sapiens DU 145 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
- CRISPRi proliferation screen of multiple loci in NCI-H460Homo sapiens NCI-H460 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
- CRISPRi proliferation screen of multiple loci in A549Homo sapiens A549 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
- CRISPRi proliferation screen of multiple loci in MDA-MB-231Homo sapiens MDA-MB-231 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
- CRISPRi proliferation screen of multiple loci in MCF-7Homo sapiens MCF-7 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
- CRISPRi proliferation screen of multiple loci in HepG2Homo sapiens HepG2 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
- CRISPRi proliferation screen of multiple loci in SW620Homo sapiens SW620 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
- CRISPRi proliferation screen of multiple loci in HCT116Homo sapiens HCT116 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
- CRISPRi proliferation screen of multiple loci in K562Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
- CRISPRi proliferation screen in OCI-AML2Functional characterization series of CRISPRi (dCas9-KRAB) growth screen targeting putative essential DHSs in K562. (validation screen in OCI-AML2).Assays: proliferation CRISPR screenLab: Tim Reddy, DukeProject: ENCODETiling modality: sparse peak
- CRISPRi proliferation screen in K562Functional characterization series of CRISPRi (dCas9-KRAB) growth screen targeting putative essential DHSs in K562 .(validation screen in K562).Assays: proliferation CRISPR screenLab: Tim Reddy, DukeProject: ENCODETiling modality: sparse peak
- CRISPRi proliferation screen in K562Functional characterization series of CRISPRi (dCas9-KRAB) growth screen targeting all previously identified open chromatin regions (DHSs) in K562. (Discovery screen).Assays: proliferation CRISPR screenLab: Tim Reddy, DukeProject: ENCODETiling modality: peak tiling
- CRISPRi proliferation screen in K562Functional characterization series for CRISPRi/dCas9-RYBP sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Assays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: DNase hypersensitive sitesTiling modality: sparse peak
- CRISPRi proliferation screen in K562Functional characterization series for CRISPRi/dCas9-KRAB-WSR7EEE sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Assays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: DNase hypersensitive sitesTiling modality: sparse peak
- CRISPRi proliferation screen in K562Functional characterization series for CRISPRi/dCas9-KRAB-MGA1-MGA2 sparse-tiling proliferation screens at ~7500 cCREs around ~450 essential genes in K562Assays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: DNase hypersensitive sitesTiling modality: sparse peak
- CRISPRi proliferation screen in K562Functional characterization series for dCas9-ZNF705-KRAB/CRISPRi tiling proliferation screens at a subset of cCREs around essential genesAssays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: DNase hypersensitive sitesTiling modality: peak tiling
- CRISPRi proliferation screen in K562Functional characterization series for dCas9-RYBP/CRISPRi tiling proliferation screens at a subset of cCREs around essential genesAssays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: DNase hypersensitive sitesTiling modality: peak tiling
- CRISPRi proliferation screen in K562Functional characterization series for dCas9-KRAB-WSR7EEE/CRISPRi tiling proliferation screens at a subset of cCREs around essential genesAssays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: DNase hypersensitive sitesTiling modality: peak tiling
- CRISPRi proliferation screen in K562Functional characterization series for dCas9-KRAB/CRISPRi tiling proliferation screens at a subset of cCREs around essential genesAssays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: DNase hypersensitive sitesTiling modality: peak tiling
- CRISPR dCas proliferation screen in K562Functional characterization series for dCas9 tiling proliferation screens at a subset of cCREs around essential genesAssays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: DNase hypersensitive sitesTiling modality: peak tiling
- CRISPR cutting proliferation screen of CTCF locus in K562Functional characterization series for Cas9/CRISPR fine-mapping proliferation screens at hit and non-hit CTCF motifs in loop anchors (and their partner anchors) from the CTCF growth screenAssays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: TF binding sitesLoci: CTCFTiling modality: peak tiling
- CRISPR dCas proliferation screen of CTCF locus in K562Functional characterization series for dCas9/CRISPRd proliferation screens at CTCF motifs in loop anchorsAssays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peak
- CRISPRa proliferation screen of CTCF locus in K562Functional characterization series for dCas9-VPR/CRISPRa proliferation screens at CTCF motifs in loop anchorsAssays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peak
- CRISPR cutting proliferation screen of CTCF locus in K562Functional characterization series for Cas9/CRISPRk proliferation screens at CTCF motifs in loop anchorsAssays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peak
- CRISPRi proliferation screen of CTCF locus in K562Functional characterization series for dCas9-KRAB/CRISPRi proliferation screens at CTCF motifs in loop anchorsAssays: proliferation CRISPR screenLab: Will Greenleaf, StanfordProject: ENCODEElements selection method: TF binding sitesLoci: CTCFTiling modality: sparse peak
- CRISPR dCas proliferation screen of multiple loci in K562Functional characterization series for tiling, dCas9/CRISPRd proliferation screens at the GATA1 locus
- CRISPRa proliferation screen of multiple loci in K562Functional characterization series for tiling, dCas9-VPR/CRISPRa proliferation screens at the GATA1 locus
- CRISPR cutting proliferation screen of multiple loci in K562Functional characterization series for tiling, Cas9/CRISPRk proliferation screens at the GATA1 locus
- CRISPRi proliferation screen of multiple loci in K562Functional characterization series for tiling, dCas9-KRAB/CRISPRi proliferation screens at the GATA1 locus
- CRISPR cutting proliferation screen of MYC locus in K562Homo sapiens K562 genetically modified (insertion) using transduction (low MOI), using CRISPR cutting (sgRNA) for MYC locusAssays: proliferation CRISPR screenLab: Yin Shen, UCSFProject: ENCODELoci: MYCTiling modality: peak tiling
- CRISPR cutting proliferation screen of GATA1 locus in K562Homo sapiens K562 genetically modified (insertion) using transduction (low MOI), using CRISPR cutting (sgRNA) for GATA1 locusAssays: proliferation CRISPR screenLab: Yin Shen, UCSFProject: ENCODELoci: GATA1Tiling modality: peak tiling
- CRISPRi proliferation screen in K562K562 cell line genetically modified (insertion) using transduction, genetically modified (CRISPRi) using CRISPRAssays: proliferation CRISPR screenLab: Bing Ren, UCSDProject: ENCODEElements selection method: histone modificationsTiling modality: peak tiling
- CRISPRi proliferation screen in HCT116HCT116 cell line genetically modified (insertion) using transduction, genetically modified (CRISPRi) using CRISPRAssays: proliferation CRISPR screenLab: Bing Ren, UCSDProject: ENCODEElements selection method: histone modificationsTiling modality: peak tiling