ENCODE Software
Software tools implemented and developed by the consortium for computational analysis
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- scPOST — sourceSimulation of single-cell datasets for power analyses that estimate power to detect cell state frequency shifts between conditions (e.g. an expansion of a cell state in disease vs. healthy), as described in our manuscript “Maximizing statistical power to detect clinically associated cell states with scPOST”.Software type: other
- cdr3-QTL — sourceWe tested associations between HLA genotypes and TCR-CDR3 amino acid compositions. We treated the amino acid composition of CDR3 as a quantitative trait, and tested its association with HLA genotype; we call this CDR3 quantitative trait loci analysis (cdr3-QTL), as described in our manuscript “HLA autoimmune risk alleles restrict the hypervariable region of T cell receptors”.Software type: other