ENCBS357GME / cell line

Summary

Status
released
Term name
K562
Summary
Homo sapiens K562 cell line genetically modified (deletion) using TALEN
Description
TALEN-mediated heterozygous DHS deletion in K562.

Attribution

ENCODE3 project
Lab
John Stamatoyannopoulos, UW
Award PI
John Stamatoyannopoulos, UW
Submitted by
Michael Buckley
Project
ENCODE
Aliases
john-stamatoyannopoulos:DS28346
Submitter comment
The genetic modification modeling for this Biosample is incomplete. The two GMs listed will form 1 cut site. The submitting lab will submit the other cut site, and at that time, the GMs will be merged into one.

Genetic modifications

Accession
Category
Purpose
Method
Site
ENCGM092PHVdeletioncharacterizationTALEN
Coordinates
hg19 chr9:100723434-100723450
ENCGM120CRZdeletioncharacterizationTALEN
Coordinates
hg19 chr9:100723471-100723487

Donor information

Status
released
Accession
ENCDO000AAD
Aliases
encode:donor of K562, bradley-bernstein:Donor of K562 cells
Donor external identifiers
Species
Homo sapiens
Life stage
adult
Age
53 years
Sex
female
Health status
chronic myelogenous leukemia (CML)
References