ENCBS031FXR / cell line

Summary

Status
released
Term name
K562
Summary
Homo sapiens K562 cell line genetically modified (deletion) using TALEN
Description
TALEN-mediated homozygous DHS deletion in K562.

Attribution

ENCODE3 project
Lab
John Stamatoyannopoulos, UW
Award PI
John Stamatoyannopoulos, UW
Submitted by
Michael Buckley
Project
ENCODE
External resources
Aliases
john-stamatoyannopoulos:DS29674A
Submitter comment
The genetic modification modeling for this Biosample is incomplete. The two GMs listed will form 1 cut site. The submitting lab will submit the other cut site, and at that time, the GMs will be merged into one.

Genetic modifications

AccessionCategoryPurposeMethodSite
ENCGM833PISdeletioncharacterizationTALEN
Coordinates
hg19 chr9:4763178-4763197
ENCGM166BWLdeletioncharacterizationTALEN
Coordinates
hg19 chr9:4763217-4763233

Donor information

Status
released
Accession
ENCDO000AAD
Aliases
encode:donor of K562, bradley-bernstein:Donor of K562 cells
Donor external identifiers
Species
Homo sapiens
Life stage
adult
Age
53 years
Sex
female
Health status
chronic myelogenous leukemia (CML)
References