ENCAB746WGD
Antibody against Drosophila melanogaster Bre1
Drosophila melanogaster
any cell type or tissue
awaiting characterization
- Status
- released
- Source (vendor)
- SDIX, LLC
- Product ID
- sdix Bre1 modENCODE antibody 1
- Lot ID
- unknown
- Characterized targets
- Bre1 (Drosophila melanogaster)
- Host
- rabbit
- Clonality
- polyclonal
- Purification
- affinity
- Antigen description
- E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-117' of histone H2B. H2B 'Lys-117' ubiquitination gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. Required for the expression of Notch target genes in development by affecting the levels of Su(H) (Suppressor of hairless protein ) in imaginal disk cells and stimulating the Su(H)-mediated transcription of Notch-specific genes. Accession Number: AAF50744
- Antigen sequence
- Amino Acids 50-149
- External resources